Cell atlas - CSNK1G1 - The Human Protein Atlas

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CSNK1G1

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	CSNK1G1
Gene description	Casein kinase 1, gamma 1
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	15
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA018209
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA018209	A-431	Cytosol
	HPA018209	U-2 OS	Cytosol
	HPA018209	U-251 MG	Cytosol

GENE INFORMATION
Gene name	CSNK1G1 (HGNC Symbol)
Synonyms	CK1gamma1
Description	Casein kinase 1, gamma 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the casein kinase I gene family. The encoded protein is a serine/threonine kinase that phosphorylates acidic proteins, and participates in pathways for cell growth. [provided by RefSeq, Nov 2011]
Chromosome	15
Cytoband	q22.31
Chromosome location (bp)	64165517 - 64356259
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169118 (version 83.38)
Entrez gene	53944
UniProt	Q9HCP0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HCP0
Antibodypedia	CSNK1G1 antibodies

PROTEIN BROWSER

CSNK1G1-001	CSNK1G1-002	CSNK1G1-004	CSNK1G1-005	CSNK1G1-006	CSNK1G1-007	CSNK1G1-008	CSNK1G1-009	CSNK1G1-010	CSNK1G1-011	CSNK1G1-012	CSNK1G1-016	CSNK1G1-017	CSNK1G1-018	CSNK1G1-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CSNK1G1-001 ENSP00000305777 ENST00000303052	Q9HCP0 [Direct mapping] Casein kinase I isoform gamma-1 A0A024R5W3 [Target identity:100%; Query identity:100%] HCG2004507, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Kinases CK1 Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0001948 [glycoprotein binding] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0006897 [endocytosis] GO:0008360 [regulation of cell shape] GO:0016055 [Wnt signaling pathway] GO:0018105 [peptidyl-serine phosphorylation] GO:0042277 [peptide binding] GO:0046777 [protein autophosphorylation] GO:0051219 [phosphoprotein binding] Show all	422 aa 48.5 kDa	No	0
CSNK1G1-002 ENSP00000475724 ENST00000607537	U3KQB3 [Direct mapping] Casein kinase I isoform gamma-1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0006897 [endocytosis] GO:0008360 [regulation of cell shape] GO:0016055 [Wnt signaling pathway] GO:0018105 [peptidyl-serine phosphorylation] Show all	475 aa 54.5 kDa	No	0
CSNK1G1-004 ENSP00000489116 ENST00000634811		MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	459 aa 52.6 kDa	No	0
CSNK1G1-005 ENSP00000489233 ENST00000634654		MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	459 aa 52.6 kDa	No	0
CSNK1G1-006 ENSP00000489415 ENST00000634847		MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	422 aa 48.6 kDa	No	0
CSNK1G1-007 ENSP00000475686 ENST00000606793	U3KQA5 [Direct mapping] Uncharacterized protein Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	422 aa 48.6 kDa	No	0
CSNK1G1-008 ENSP00000489165 ENST00000635142		MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	430 aa 49.5 kDa	No	0
CSNK1G1-009 ENSP00000476088 ENST00000561349	U3KQN9 [Direct mapping] Uncharacterized protein Q8IXA3 [Target identity:100%; Query identity:100%] Casein kinase I gamma 1 isoform; HCG2004507, isoform CRA_d Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	438 aa 50.3 kDa	No	0
CSNK1G1-010 ENSP00000489050 ENST00000634302		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] Show all	204 aa 23.5 kDa	No	0
CSNK1G1-011 ENSP00000489046 ENST00000635514		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	138 aa 15.5 kDa	No	0
CSNK1G1-012 ENSP00000489277 ENST00000635270		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	183 aa 20.8 kDa	No	0
CSNK1G1-016 ENSP00000488990 ENST00000634909		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] Show all	173 aa 19.9 kDa	No	0
CSNK1G1-017 ENSP00000489310 ENST00000634722		Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] Show all	158 aa 17.7 kDa	No	1
CSNK1G1-018 ENSP00000489090 ENST00000635414		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] Show all	67 aa 7.5 kDa	No	0
CSNK1G1-019 ENSP00000489172 ENST00000635230		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] Show all	36 aa 3.8 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.