Tissue expression of UBE2V2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	UBE2V2
Gene description	Ubiquitin-conjugating enzyme E2 variant 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	UBE2V2 (HGNC Symbol)
Synonyms	DDVit-1, EDPF-1, MMS2, UEV-2
Description	Ubiquitin-conjugating enzyme E2 variant 2 (HGNC Symbol)
Entrez gene summary	Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	q11.21
Chromosome location (bp)	48008400 - 48064708
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169139 (version 83.38)
Entrez gene	7336
UniProt	Q15819 (UniProt - Evidence at protein level)
neXtProt	NX_Q15819
Antibodypedia	UBE2V2 antibodies

PROTEIN BROWSER

UBE2V2-001	UBE2V2-002	UBE2V2-006	UBE2V2-007	UBE2V2-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UBE2V2-001 ENSP00000428209 ENST00000523111	Q15819 [Direct mapping] Ubiquitin-conjugating enzyme E2 variant 2 A0M8W4 [Target identity:100%; Query identity:100%] Ubiquitin-conjugating enzyme E2 variant 2; Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_b; cDNA, FLJ93989, Homo sapiens ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2),mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0000724 [double-strand break repair via homologous recombination] GO:0000729 [DNA double-strand break processing] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006281 [DNA repair] GO:0006282 [regulation of DNA repair] GO:0006289 [nucleotide-excision repair] GO:0006301 [postreplication repair] GO:0006302 [double-strand break repair] GO:0006303 [double-strand break repair via nonhomologous end joining] GO:0008283 [cell proliferation] GO:0016567 [protein ubiquitination] GO:0031372 [UBC13-MMS2 complex] GO:0031625 [ubiquitin protein ligase binding] GO:0042275 [error-free postreplication DNA repair] GO:0061630 [ubiquitin protein ligase activity] GO:0061631 [ubiquitin conjugating enzyme activity] GO:0070062 [extracellular exosome] GO:0070534 [protein K63-linked ubiquitination] GO:0070911 [global genome nucleotide-excision repair] Show all	145 aa 16.4 kDa	No	0
UBE2V2-002 ENSP00000429419 ENST00000520809	G3V113 [Direct mapping] Ubiquitin-conjugating enzyme E2 variant 2; Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006301 [postreplication repair] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0070534 [protein K63-linked ubiquitination] Show all	105 aa 12 kDa	No	0
UBE2V2-006 ENSP00000429886 ENST00000517630	G3V113 [Direct mapping] Ubiquitin-conjugating enzyme E2 variant 2; Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006301 [postreplication repair] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0070534 [protein K63-linked ubiquitination] Show all	105 aa 12 kDa	No	0
UBE2V2-007 ENSP00000428818 ENST00000521346	G3V113 [Direct mapping] Ubiquitin-conjugating enzyme E2 variant 2; Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006301 [postreplication repair] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0070534 [protein K63-linked ubiquitination] Show all	105 aa 12 kDa	No	0
UBE2V2-009 ENSP00000430019 ENST00000523432	H0YBP9 [Direct mapping] Ubiquitin-conjugating enzyme E2 variant 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006301 [postreplication repair] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0070534 [protein K63-linked ubiquitination] Show all	109 aa 12.3 kDa	No	0