Expression of GSG1L in cancer - Summary - The Human Protein Atlas

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GSG1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GSG1L
Gene description	GSG1-like
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Group enriched (HMC-1, THP-1)
HPA (normal tissue):	Tissue enhanced (cerebral cortex, heart muscle)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membranous expression in several tissues, most abundant in brain.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending retesting.
Reliability score	Approved based on 1 antibody. HPA014479
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA014479

GENE INFORMATION
Gene name	GSG1L (HGNC Symbol)
Synonyms	KTSR5831, MGC18079, PRO19651
Description	GSG1-like (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.1
Chromosome location (bp)	27787535 - 28063509
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169181 (version 83.38)
Entrez gene	146395
UniProt	Q6UXU4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UXU4
Antibodypedia	GSG1L antibodies

PROTEIN BROWSER

GSG1L-001	GSG1L-002	GSG1L-003	GSG1L-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GSG1L-001 ENSP00000370282 ENST00000380897	Q6UXU4 [Direct mapping] Germ cell-specific gene 1-like protein Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] Show all	176 aa 20.6 kDa	No	2
GSG1L-002 ENSP00000394954 ENST00000447459	Q6UXU4 [Direct mapping] Germ cell-specific gene 1-like protein Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0032279 [asymmetric synapse] Show all	331 aa 36.8 kDa	Yes	3
GSG1L-003 ENSP00000379074 ENST00000395724	Q6UXU4 [Direct mapping] Germ cell-specific gene 1-like protein Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] Show all	280 aa 31.3 kDa	Yes	1
GSG1L-004 ENSP00000454880 ENST00000569166	Q6UXU4 [Direct mapping] Germ cell-specific gene 1-like protein Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] Show all	194 aa 22.7 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.