Cell atlas - RNASE6 - The Human Protein Atlas

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RNASE6

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RNASE6
Gene description	Ribonuclease, RNase A family, k6
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (RPMI-8226)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (RPMI-8226) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RNASE6 (HGNC Symbol)
Synonyms	RAD1, RNS6
Description	Ribonuclease, RNase A family, k6 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	20781051 - 20782467
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169413 (version 83.38)
Entrez gene	6039
UniProt	Q93091 (UniProt - Evidence at transcript level)
neXtProt	NX_Q93091
Antibodypedia	RNASE6 antibodies

PROTEIN BROWSER

RNASE6-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RNASE6-002 ENSP00000302046 ENST00000304677	Q93091 [Direct mapping] Ribonuclease K6 Q6IB39 [Target identity:100%; Query identity:100%] RNASE6 protein; Ribonuclease A D1; Ribonuclease, RNase A family, k6, isoform CRA_a; cDNA, FLJ94144, Homo sapiens ribonuclease, RNase A family, k6 (RNASE6), mRNA Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004519 [endonuclease activity] GO:0004540 [ribonuclease activity] GO:0005576 [extracellular region] GO:0006401 [RNA catabolic process] GO:0006952 [defense response] GO:0070062 [extracellular exosome] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] GO:0090501 [RNA phosphodiester bond hydrolysis] Show all	150 aa 17.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.