Expression of SLC38A11 in cancer - Summary - The Human Protein Atlas

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SLC38A11

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SLC38A11
Gene description	Solute carrier family 38, member 11
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (prostate cancer)
HPA (cell line):	Cell line enriched (BJ hTERT+)
HPA (normal tissue):	Tissue enhanced (epididymis, gallbladder)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA043432
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043432

GENE INFORMATION
Gene name	SLC38A11 (HGNC Symbol)
Synonyms	AVT2, FLJ39822
Description	Solute carrier family 38, member 11 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q24.3
Chromosome location (bp)	164896186 - 164955525
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000169507 (version 83.38)
Entrez gene	151258
UniProt	Q08AI6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q08AI6
Antibodypedia	SLC38A11 antibodies

PROTEIN BROWSER

SLC38A11-001	SLC38A11-002	SLC38A11-003	SLC38A11-009	SLC38A11-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC38A11-001 ENSP00000306178 ENST00000303735	Q08AI6 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 11 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005783 [endoplasmic reticulum] GO:0006814 [sodium ion transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	384 aa 42.4 kDa	No	9
SLC38A11-002 ENSP00000387345 ENST00000409058	B8ZZ86 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005783 [endoplasmic reticulum] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	437 aa 48.3 kDa	No	>9
SLC38A11-003 ENSP00000386272 ENST00000409149	Q08AI6 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 11 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005783 [endoplasmic reticulum] GO:0006814 [sodium ion transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	406 aa 44.8 kDa	No	>9
SLC38A11-009 ENSP00000386774 ENST00000409662	Q08AI6 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 11 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005783 [endoplasmic reticulum] GO:0006814 [sodium ion transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	406 aa 44.8 kDa	No	>9
SLC38A11-010 ENSP00000401448 ENST00000424914	H7C1P1 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005783 [endoplasmic reticulum] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	151 aa 16.4 kDa	Yes	3

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.