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TACR3

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GENERAL INFORMATION

Gene name

 TACR3

Gene description

 Tachykinin receptor 3

Protein class

 Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enriched (BEWO)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (BEWO)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 TACR3 (HGNC Symbol)

Synonyms

 NK3R

Description

 Tachykinin receptor 3 (HGNC Symbol)

Entrez gene summary

 This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 q24

Chromosome location (bp)

 103586031 - 103719816

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000169836 (version 83.38)

Entrez gene

 6870

UniProt

 P29371 (UniProt - Evidence at protein level)

neXtProt

 NX_P29371

Antibodypedia

 TACR3 antibodies

PROTEIN BROWSER
TACR3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TACR3-001
ENSP00000303325
ENST00000304883
P29371 [Direct mapping]
Neuromedin-K receptor
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Disease related genes
Potential drug targets
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0004995 [tachykinin receptor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007217 [tachykinin receptor signaling pathway]
GO:0007568 [aging]
GO:0010460 [positive regulation of heart rate]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0032355 [response to estradiol]
GO:0032590 [dendrite membrane]
GO:0032809 [neuronal cell body membrane]
GO:0042053 [regulation of dopamine metabolic process]
GO:0042220 [response to cocaine]
GO:0042538 [hyperosmotic salinity response]
GO:0043278 [response to morphine]
GO:0045777 [positive regulation of blood pressure]
GO:0060259 [regulation of feeding behavior]
GO:0070474 [positive regulation of uterine smooth muscle contraction]
Show all
 465 aa
52.2 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.