Cell atlas - SYAP1 - The Human Protein Atlas

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SYAP1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS CUSTOM DATA

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Golgi apparatus
	Nucleoplasm

Human cell
	Cytosol
	Golgi Apparatus
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SYAP1
Gene description	Synapse associated protein 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the cytosol & nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (validated)
Additional location	In addition localized to the Nucleoplasm (supported), Cytosol (supported)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA000882 , HPA048047
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ASSAYS

RNA expression

Human cells

Custom data

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the cytosol & nucleoplasm.

Main location

Golgi apparatus (validated)

Additional location

Nucleoplasm (supported), Cytosol (supported)


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Antibody	Cell line	Location
HPA048047	A-431	Nucleoplasm
		Golgi apparatus
		Cytosol
HPA048047	HEK 293	Nucleoplasm
		Golgi apparatus
		Cytosol
HPA048047	U-2 OS	Nucleoplasm
		Golgi apparatus
		Cytosol
HPA000882	A-431	Nucleoplasm
		Golgi apparatus
		Cytosol
HPA000882	U-2 OS	Nucleoplasm
		Golgi apparatus
		Cytosol
HPA000882	U-251 MG	Nucleoplasm
		Golgi apparatus
		Cytosol

CUSTOM DATA


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Thumbnail	Antibody	Cell line	Assay	Description
	HPA000882	U-2 OS	Image	Co-localization with the cis-Golgi marker GM130/GOLGA2 (RRID:AB_398141) for a refined protein localization within the Golgi apparatus in U-2 OS cells. SYAP1 localizes to the Golgi apparatus, but not to the cis-Golgi compartment.

GENE INFORMATION
Gene name	SYAP1 (HGNC Symbol)
Synonyms	FLJ14495, PRO3113
Description	Synapse associated protein 1 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	p22.2
Chromosome location (bp)	16719632 - 16765336
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169895 (version 83.38)
Entrez gene	94056
UniProt	Q96A49 (UniProt - Evidence at protein level)
neXtProt	NX_Q96A49
Antibodypedia	SYAP1 antibodies

PROTEIN BROWSER

SYAP1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SYAP1-001 ENSP00000369500 ENST00000380155	Q96A49 [Direct mapping] Synapse-associated protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0070062 [extracellular exosome] Show all	352 aa 39.9 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.