Expression of S100G in cancer - Summary - The Human Protein Atlas

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S100G

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	S100G
Gene description	S100 calcium binding protein G
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (breast cancer, renal cancer)
HPA (cell line):	Cell line enhanced (RPMI-8226)
HPA (normal tissue):	Tissue enriched (duodenum)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective expression in the small intestine.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA055873 , CAB017688
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (breast cancer, renal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055873	CAB017688

GENE INFORMATION
Gene name	S100G (HGNC Symbol)
Synonyms	CABP1, CABP9K, CALB3
Description	S100 calcium binding protein G (HGNC Symbol)
Entrez gene summary	This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	p22.2
Chromosome location (bp)	16650158 - 16654670
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169906 (version 83.38)
Entrez gene	795
UniProt	P29377 (UniProt - Inferred from homology)
neXtProt	NX_P29377
Antibodypedia	S100G antibodies

PROTEIN BROWSER

S100G-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
S100G-001 ENSP00000369547 ENST00000380200	P29377 [Direct mapping] Protein S100-G Show all	Predicted intracellular proteins Show all	GO:0005499 [vitamin D binding] GO:0005509 [calcium ion binding] GO:0016323 [basolateral plasma membrane] GO:0016324 [apical plasma membrane] Show all	79 aa 9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.