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TRAPPC1

GENERAL INFORMATION

Gene name

 TRAPPC1

Gene description

 Trafficking protein particle complex 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA052398
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA052398

GENE INFORMATION

Gene name

 TRAPPC1 (HGNC Symbol)

Synonyms

 BET5, MUM2

Description

 Trafficking protein particle complex 1 (HGNC Symbol)

Entrez gene summary

 This gene product plays a role in vesicular transport of proteins to the Golgi apparatus from the endoplasmic reticulum. The encoded protein is a component of the multisubunit transport protein particle (TRAPP) complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Chromosome

 17

Cytoband

 p13.1

Chromosome location (bp)

 7930345 - 7932123

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000170043 (version 83.38)

Entrez gene

 58485

UniProt

 Q9Y5R8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y5R8

Antibodypedia

 TRAPPC1 antibodies

PROTEIN BROWSER
TRAPPC1-001
TRAPPC1-002
TRAPPC1-006
TRAPPC1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRAPPC1-001
ENSP00000302783
ENST00000303731
Q9Y5R8 [Direct mapping]
Trafficking protein particle complex subunit 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0005801 [cis-Golgi network]
GO:0005829 [cytosol]
GO:0006810 [transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030008 [TRAPP complex]
GO:0043547 [positive regulation of GTPase activity]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
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 145 aa
16.8 kDa 		No 0
TRAPPC1-002
ENSP00000460761
ENST00000572656
I3L3V5 [Direct mapping]
Trafficking protein particle complex subunit 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005801 [cis-Golgi network]
GO:0006810 [transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030008 [TRAPP complex]
GO:0043547 [positive regulation of GTPase activity]
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 75 aa
9.1 kDa 		No 0
TRAPPC1-006
ENSP00000460674
ENST00000571947
I3L3S0 [Direct mapping]
Trafficking protein particle complex subunit 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005801 [cis-Golgi network]
GO:0006810 [transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030008 [TRAPP complex]
GO:0043547 [positive regulation of GTPase activity]
Show all
 95 aa
11.2 kDa 		No 0
TRAPPC1-201
ENSP00000441130
ENST00000540486
Q9Y5R8 [Direct mapping]
Trafficking protein particle complex subunit 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005783 [endoplasmic reticulum]
GO:0005801 [cis-Golgi network]
GO:0005829 [cytosol]
GO:0006810 [transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0030008 [TRAPP complex]
GO:0043547 [positive regulation of GTPase activity]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0061024 [membrane organization]
Show all
 145 aa
16.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.