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KCNAB3

GENERAL INFORMATION

Gene name

 KCNAB3

Gene description

 Potassium channel, voltage gated subfamily A regulatory beta subunit 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (REH, SH-SY5Y)
HPA (normal tissue):Tissue enhanced (endometrium, smooth muscle)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 KCNAB3 (HGNC Symbol)

Synonyms

 AKR6A9, KCNA3B

Description

 Potassium channel, voltage gated subfamily A regulatory beta subunit 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. [provided by RefSeq, May 2012]

Chromosome

 17

Cytoband

 p13.1

Chromosome location (bp)

 7921859 - 7929803

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000170049 (version 83.38)

Entrez gene

 9196

UniProt

 O43448 (UniProt - Evidence at transcript level)

neXtProt

 NX_O43448

Antibodypedia

 KCNAB3 antibodies

PROTEIN BROWSER
KCNAB3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KCNAB3-001
ENSP00000302719
ENST00000303790
O43448 [Direct mapping]
Voltage-gated potassium channel subunit beta-3
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0005249 [voltage-gated potassium channel activity]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0006813 [potassium ion transport]
GO:0007268 [synaptic transmission]
GO:0015459 [potassium channel regulator activity]
GO:0016021 [integral component of membrane]
GO:0034765 [regulation of ion transmembrane transport]
GO:0071805 [potassium ion transmembrane transport]
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 404 aa
43.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.