Expression of CCDC144A in cancer - Summary - The Human Protein Atlas

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CCDC144A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC144A
Gene description	Coiled-coil domain containing 144A
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression of varying intensity.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 2 antibodies. HPA022996 , HPA047851
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA022996	HPA047851

GENE INFORMATION
Gene name	CCDC144A (HGNC Symbol)
Synonyms	FLJ43983, KIAA0565
Description	Coiled-coil domain containing 144A (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p11.2
Chromosome location (bp)	16689537 - 16777881
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170160 (version 83.38)
Entrez gene	9720
UniProt	A2RUR9 (UniProt - Evidence at protein level)
neXtProt	NX_A2RUR9
Antibodypedia	CCDC144A antibodies

PROTEIN BROWSER

CCDC144A-001	CCDC144A-002	CCDC144A-006	CCDC144A-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC144A-001 ENSP00000382215 ENST00000399273	C9JT67 [Direct mapping] Coiled-coil domain-containing protein 144A; Uncharacterized protein Show all	Predicted intracellular proteins Show all		1425 aa 165.1 kDa	No	0
CCDC144A-002 ENSP00000344740 ENST00000340621	A6NJB5 [Direct mapping] Coiled-coil domain-containing protein 144A Show all	Predicted intracellular proteins Show all		571 aa 64.8 kDa	No	0
CCDC144A-006 ENSP00000398774 ENST00000420937	C9JAY6 [Direct mapping] Coiled-coil domain-containing protein 144A Show all	Predicted intracellular proteins Show all		178 aa 20.3 kDa	No	0
CCDC144A-013 ENSP00000353717 ENST00000360524	A2RUR9 [Direct mapping] Coiled-coil domain-containing protein 144A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all		1427 aa 165.1 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.