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RNA cell line category: Group enriched (HEL, K-562)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATION
Gene name
GYPA (HGNC Symbol)
Synonyms
CD235a, GPA, MN, MNS
Description
Glycophorin A (MNS blood group) (HGNC Symbol)
Entrez gene summary
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]
GO:0005887 [integral component of plasma membrane] GO:0007016 [cytoskeletal anchoring at plasma membrane] GO:0009897 [external side of plasma membrane] GO:0016021 [integral component of membrane] GO:0042803 [protein homodimerization activity] GO:0047484 [regulation of response to osmotic stress]
