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Expression of cilia in fallopian tube and respiratory epithelia with luminal membrane expression in gastrointestinal tract.
ANTIBODY IHC RELIABILITY
Data reliability description
Antibody staining mainly consistent with RNA expression data. Pending external verification. Protein expression in respiratory epithelia can be correlated with lung RNA-seq data.
Distinct membranous staining with varying intensity in most colorectal cancers. Additional staining was also seen in connective tissues. Remaining cancers were generally negative.
GENE INFORMATION
Gene name
FAM161A (HGNC Symbol)
Synonyms
FLJ13305, RP28
Description
Family with sequence similarity 161, member A (HGNC Symbol)
Entrez gene summary
This gene belongs to the FAM161 family. It is expressed mainly in the retina. Mouse studies suggested that this gene is involved in development of retinal progenitors during embryogenesis, and that its activity is restricted to mature photoreceptors after birth. Mutations in this gene cause autosomal recessive retinitis pigmentosa-28. Alternatively spliced transcript variants have been identified.[provided by RefSeq, Jan 2011]