Expression of C14orf142 in cancer - Summary - The Human Protein Atlas

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C14orf142

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C14orf142
Gene description	Chromosome 14 open reading frame 142
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA051832
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and renal cancer (favourable).
Liver cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA051832

GENE INFORMATION
Gene name	C14orf142
Synonyms
Description	Chromosome 14 open reading frame 142 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.12
Chromosome location (bp)	93202894 - 93207094
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170270 (version 83.38)
Entrez gene	84520
UniProt	Q9BXV9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXV9
Antibodypedia	C14orf142 antibodies

PROTEIN BROWSER

C14orf142-001	C14orf142-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C14orf142-001 ENSP00000306320 ENST00000306954	Q9BXV9 [Direct mapping] Uncharacterized protein C14orf142 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		100 aa 10.9 kDa	No	0
C14orf142-002 ENSP00000451114 ENST00000556566	H0YJA8 [Direct mapping] Uncharacterized protein C14orf142 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		79 aa 8.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.