Expression of ELP5 in cancer - Summary - The Human Protein Atlas

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ELP5

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ELP5
Gene description	Elongator acetyltransferase complex subunit 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	14
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA023279
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023279

GENE INFORMATION
Gene name	ELP5 (HGNC Symbol)
Synonyms	C17orf81, DERP6
Description	Elongator acetyltransferase complex subunit 5 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	7251416 - 7259940
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170291 (version 83.38)
Entrez gene	23587
UniProt	Q8TE02 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TE02
Antibodypedia	ELP5 antibodies

PROTEIN BROWSER

ELP5-001	ELP5-002	ELP5-003	ELP5-004	ELP5-005	ELP5-006	ELP5-007	ELP5-009	ELP5-010	ELP5-011	ELP5-012	ELP5-013	ELP5-201	ELP5-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ELP5-001 ENSP00000379868 ENST00000396627	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	316 aa 34.8 kDa	No	0
ELP5-002 ENSP00000459835 ENST00000574993	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	279 aa 30.3 kDa	No	0
ELP5-003 ENSP00000379869 ENST00000396628	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	316 aa 34.8 kDa	No	0
ELP5-004 ENSP00000460947 ENST00000570322	I3L437 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0033588 [Elongator holoenzyme complex] Show all	245 aa 26.3 kDa	No	0
ELP5-005 ENSP00000461489 ENST00000574255	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	179 aa 19.7 kDa	No	0
ELP5-006 ENSP00000459897 ENST00000573699	I3L2T0 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0033588 [Elongator holoenzyme complex] Show all	210 aa 22.7 kDa	No	0
ELP5-007 ENSP00000459633 ENST00000573657	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	179 aa 19.7 kDa	No	0
ELP5-009 ENSP00000461890 ENST00000574841	I3NI50 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		43 aa 4.8 kDa	No	0
ELP5-010 ENSP00000460596 ENST00000573513	I3L3N8 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0033588 [Elongator holoenzyme complex] Show all	230 aa 25 kDa	No	0
ELP5-011 ENSP00000458691 ENST00000570500	I3L1A8 [Direct mapping] Elongator complex protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0033588 [Elongator holoenzyme complex] Show all	95 aa 10.7 kDa	No	0
ELP5-012 ENSP00000459248 ENST00000572104	I3L200 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		108 aa 11.6 kDa	No	0
ELP5-013 ENSP00000459010 ENST00000576496	I3L1Q3 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0033588 [Elongator holoenzyme complex] Show all	262 aa 28.7 kDa	No	0
ELP5-201 ENSP00000346412 ENST00000354429	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	316 aa 34.8 kDa	No	0
ELP5-202 ENSP00000349111 ENST00000356683	Q8TE02 [Direct mapping] Elongator complex protein 5 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030335 [positive regulation of cell migration] GO:0033588 [Elongator holoenzyme complex] Show all	279 aa 30.3 kDa	No	0

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The Human Protein Atlas

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