Fields »
ABOUT
HELP
BLOG
GABARAP

GENERAL INFORMATION

Gene name

 GABARAP

Gene description

 GABA(A) receptor-associated protein

Protein class

 Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GABARAP (HGNC Symbol)

Synonyms

 ATG8A, MM46

Description

 GABA(A) receptor-associated protein (HGNC Symbol)

Entrez gene summary

 Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 p13.1

Chromosome location (bp)

 7240014 - 7242770

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000170296 (version 83.38)

Entrez gene

 11337

UniProt

 O95166 (UniProt - Evidence at protein level)

neXtProt

 NX_O95166

Antibodypedia

 GABARAP antibodies

PROTEIN BROWSER
GABARAP-001
GABARAP-002
GABARAP-003
GABARAP-004
GABARAP-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GABARAP-001
ENSP00000306866
ENST00000302386
O95166 [Direct mapping]
Gamma-aminobutyric acid receptor-associated protein
Q6IAW1 [Target identity:100%; Query identity:100%]
GABA(A) receptor-associated protein; GABARAP protein; HCG1987397, isoform CRA_b
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000139 [Golgi membrane]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000407 [pre-autophagosomal structure]
GO:0000421 [autophagosome membrane]
GO:0000422 [mitophagy]
GO:0005515 [protein binding]
GO:0005764 [lysosome]
GO:0005776 [autophagosome]
GO:0005790 [smooth endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0005886 [plasma membrane]
GO:0005930 [axoneme]
GO:0006605 [protein targeting]
GO:0007268 [synaptic transmission]
GO:0008017 [microtubule binding]
GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors]
GO:0015031 [protein transport]
GO:0015629 [actin cytoskeleton]
GO:0016236 [macroautophagy]
GO:0019898 [extrinsic component of membrane]
GO:0031410 [cytoplasmic vesicle]
GO:0031625 [ubiquitin protein ligase binding]
GO:0044297 [cell body]
GO:0044804 [nucleophagy]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048487 [beta-tubulin binding]
GO:0050811 [GABA receptor binding]
GO:0061025 [membrane fusion]
Show all
 117 aa
13.9 kDa 		No 0
GABARAP-002
ENSP00000458476
ENST00000573928
H6UMI1 [Direct mapping]
GABARAP-a; Gamma-aminobutyric acid receptor-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0005829 [cytosol]
GO:0008017 [microtubule binding]
GO:0019898 [extrinsic component of membrane]
GO:0044804 [nucleophagy]
GO:0061025 [membrane fusion]
Show all
 98 aa
11.7 kDa 		No 0
GABARAP-003
ENSP00000459345
ENST00000571253
I3L236 [Direct mapping]
Gamma-aminobutyric acid receptor-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0005829 [cytosol]
GO:0008017 [microtubule binding]
GO:0019898 [extrinsic component of membrane]
GO:0044804 [nucleophagy]
GO:0061025 [membrane fusion]
Show all
 27 aa
3.3 kDa 		No 0
GABARAP-004
ENSP00000461882
ENST00000571129
I3L236 [Direct mapping]
Gamma-aminobutyric acid receptor-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0005829 [cytosol]
GO:0008017 [microtubule binding]
GO:0019898 [extrinsic component of membrane]
GO:0044804 [nucleophagy]
GO:0061025 [membrane fusion]
Show all
 27 aa
3.3 kDa 		No 0
GABARAP-005
ENSP00000460855
ENST00000577035
I3L236 [Direct mapping]
Gamma-aminobutyric acid receptor-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0005829 [cytosol]
GO:0008017 [microtubule binding]
GO:0019898 [extrinsic component of membrane]
GO:0044804 [nucleophagy]
GO:0061025 [membrane fusion]
Show all
 27 aa
3.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.