Tissue expression of TCAF2 - Summary - The Human Protein Atlas

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TCAF2

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TCAF2
Gene description	TRPM8 channel-associated factor 2
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA038756 , HPA038758
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	TCAF2 (HGNC Symbol)
Synonyms	FAM115C, FAM139A, FLJ40722
Description	TRPM8 channel-associated factor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q35
Chromosome location (bp)	143620950 - 143730409
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170379 (version 83.38)
Entrez gene	285966
UniProt	A6NFQ2 (UniProt - Evidence at protein level)
neXtProt	NX_A6NFQ2
Antibodypedia	TCAF2 antibodies

PROTEIN BROWSER

TCAF2-001	TCAF2-002	TCAF2-003	TCAF2-004	TCAF2-005	TCAF2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCAF2-001 ENSP00000404265 ENST00000441159	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	919 aa 100.9 kDa	No	0
TCAF2-002 ENSP00000349902 ENST00000357344	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	845 aa 92 kDa	No	0
TCAF2-003 ENSP00000412724 ENST00000444908	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002244 [hematopoietic progenitor cell differentiation] GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	845 aa 92 kDa	No	0
TCAF2-004 ENSP00000389100 ENST00000411935	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	815 aa 90.6 kDa	No	0
TCAF2-005 ENSP00000431079 ENST00000518791	H0YC74 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		660 aa 72.2 kDa	No	0
TCAF2-201 ENSP00000441099 ENST00000425618	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	815 aa 90.6 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.