Cell atlas - C14orf169 - The Human Protein Atlas

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C14orf169

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli

Human cell
	Nucleoli

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GENERAL INFORMATION
Gene name	C14orf169
Gene description	Chromosome 14 open reading frame 169
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoli.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA003730
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoli.

Main location

Nucleoli (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA003730	MCF7	Nucleoli
	HPA003730	SiHa	Nucleoli
	HPA003730	U-2 OS	Nucleoli

GENE INFORMATION
Gene name	C14orf169 (HGNC Symbol)
Synonyms	FLJ21802, MAPJD, NO66
Description	Chromosome 14 open reading frame 169 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	73490964 - 73493392
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170468 (version 83.38)
Entrez gene	79697
UniProt	Q9H6W3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H6W3
Antibodypedia	C14orf169 antibodies

PROTEIN BROWSER

C14orf169-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C14orf169-003 ENSP00000477507 ENST00000304061	Q9H6W3 [Direct mapping] Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005506 [iron ion binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0006351 [transcription, DNA-templated] GO:0016706 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors] GO:0032453 [histone demethylase activity (H3-K4 specific)] GO:0034720 [histone H3-K4 demethylation] GO:0045668 [negative regulation of osteoblast differentiation] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0051864 [histone demethylase activity (H3-K36 specific)] GO:0055114 [oxidation-reduction process] GO:0070544 [histone H3-K36 demethylation] Show all	641 aa 71.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.