Cell atlas - ELOVL6 - The Human Protein Atlas

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ELOVL6

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ELOVL6
Gene description	ELOVL fatty acid elongase 6
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ELOVL6 (HGNC Symbol)
Synonyms	FLJ23378, LCE, MGC5487
Description	ELOVL fatty acid elongase 6 (HGNC Symbol)
Entrez gene summary	Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]
Chromosome	4
Cytoband	q25
Chromosome location (bp)	110045846 - 110199199
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170522 (version 83.38)
Entrez gene	79071
UniProt	Q9H5J4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H5J4
Antibodypedia	ELOVL6 antibodies

PROTEIN BROWSER

ELOVL6-001	ELOVL6-002	ELOVL6-003	ELOVL6-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ELOVL6-001 ENSP00000378105 ENST00000394607	Q9H5J4 [Direct mapping] Elongation of very long chain fatty acids protein 6 A0A024RDK5 [Target identity:100%; Query identity:100%] Elongation of very long chain fatty acids protein Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019367 [fatty acid elongation, saturated fatty acid] GO:0019432 [triglyceride biosynthetic process] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030497 [fatty acid elongation] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0042759 [long-chain fatty acid biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	265 aa 31.4 kDa	No	7
ELOVL6-002 ENSP00000304736 ENST00000302274	Q9H5J4 [Direct mapping] Elongation of very long chain fatty acids protein 6 A0A024RDK5 [Target identity:100%; Query identity:100%] Elongation of very long chain fatty acids protein Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0019367 [fatty acid elongation, saturated fatty acid] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0042759 [long-chain fatty acid biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	265 aa 31.4 kDa	No	7
ELOVL6-003 ENSP00000426086 ENST00000503885	D6RHI2 [Direct mapping] Elongation of very long chain fatty acids protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006633 [fatty acid biosynthetic process] GO:0016021 [integral component of membrane] GO:0016740 [transferase activity] Show all	108 aa 12.6 kDa	No	2
ELOVL6-004 ENSP00000425488 ENST00000506625	D6RCU0 [Direct mapping] Elongation of very long chain fatty acids protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006633 [fatty acid biosynthetic process] GO:0016021 [integral component of membrane] GO:0016740 [transferase activity] Show all	137 aa 16 kDa	No	3

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.