Expression of FAM71B in cancer - Summary - The Human Protein Atlas

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FAM71B

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM71B
Gene description	Family with sequence similarity 71, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective expression in spermatids in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 2 antibodies. HPA039478 , HPA040771
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039478	HPA040771

GENE INFORMATION
Gene name	FAM71B (HGNC Symbol)
Synonyms	MGC26988
Description	Family with sequence similarity 71, member B (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q33.3
Chromosome location (bp)	157161846 - 157166264
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170613 (version 83.38)
Entrez gene	153745
UniProt	Q8TC56 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TC56
Antibodypedia	FAM71B antibodies

PROTEIN BROWSER

FAM71B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM71B-001 ENSP00000305596 ENST00000302938	Q8TC56 [Direct mapping] Protein FAM71B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005634 [nucleus] Show all	605 aa 64.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.