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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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KIF5B
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

KIF5B

Gene description

Kinesin family member 5B

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in all tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 3 antibodies.
HPA037589 , HPA037590 , CAB009846
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

KIF5B (HGNC Symbol)

Synonyms

KNS, KNS1

Description

Kinesin family member 5B (HGNC Symbol)

Entrez gene summary

Chromosome

10

Cytoband

p11.22

Chromosome location (bp)

32009010 - 32056431

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170759 (version 83.38)

Entrez gene

3799

UniProt

P33176 (UniProt - Evidence at protein level)

neXtProt

NX_P33176

Antibodypedia

KIF5B antibodies

PROTEIN BROWSER

KIF5B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KIF5B-001
ENSP00000307078
ENST00000302418
P33176 [Direct mapping]
Kinesin-1 heavy chain
V9HW29 [Target identity:100%; Query identity:100%]
Kinesin-like protein
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Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005815 [microtubule organizing center]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0007028 [cytoplasm organization]
GO:0007411 [axon guidance]
GO:0008017 [microtubule binding]
GO:0008104 [protein localization]
GO:0008574 [ATP-dependent microtubule motor activity, plus-end-directed]
GO:0016020 [membrane]
GO:0030139 [endocytic vesicle]
GO:0030705 [cytoskeleton-dependent intracellular transport]
GO:0031982 [vesicle]
GO:0032230 [positive regulation of synaptic transmission, GABAergic]
GO:0035253 [ciliary rootlet]
GO:0035617 [stress granule disassembly]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043227 [membrane-bounded organelle]
GO:0043268 [positive regulation of potassium ion transport]
GO:0044267 [cellular protein metabolic process]
GO:0047496 [vesicle transport along microtubule]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072383 [plus-end-directed vesicle transport along microtubule]
GO:0090004 [positive regulation of establishment of protein localization to plasma membrane]
Show all
963 aa
109.7 kDa
No 0

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