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A majority of pancreatic, lung, colorectal and breast cancer displayed moderate to strong cytoplasmic positivity. Several cases of ovarian, cervical, urothelial and gastric cancers showed moderate immunoreactivity. Remaining malignancies were weakly stained or negative.
Remaining normal and malignant tissues were weakly stained or negative.
GENE INFORMATION
Gene name
SDR16C5 (HGNC Symbol)
Synonyms
RDH-E2, RDHE2
Description
Short chain dehydrogenase/reductase family 16C, member 5 (HGNC Symbol)
Entrez gene summary
RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).[supplied by OMIM, Mar 2008]