Expression of DCDC1 in cancer - Summary - The Human Protein Atlas

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DCDC1

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	DCDC1
Gene description	Doublecortin domain containing 1
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (U-266/70)
HPA (normal tissue):	Tissue enhanced (fallopian tube, testis)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	DCDC1
Synonyms
Description	Doublecortin domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the doublecortin family. The protein encoded by this gene is a hydrophilic, intracellular protein. It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization. This gene is mainly expressed in adult testis. It does not have a mouse homolog. [provided by RefSeq, Sep 2010]
Chromosome	11
Cytoband
Chromosome location (bp)	30830369 - 31369810
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170959 (version 83.38)
Entrez gene	341019
UniProt	P59894 (UniProt - Evidence at transcript level)
neXtProt	NX_P59894
Antibodypedia	DCDC1 antibodies

PROTEIN BROWSER

DCDC1-001	DCDC1-010	DCDC1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DCDC1-001 ENSP00000389792 ENST00000452803	P59894 [Direct mapping] Doublecortin domain-containing protein 1 Show all	Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	354 aa 39.9 kDa	No	0
DCDC1-010 ENSP00000472625 ENST00000597505	M0R2J8 [Direct mapping] Doublecortin domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	1783 aa 200.6 kDa	No	0
DCDC1-201 ENSP00000385936 ENST00000406071	B6ZDN3 [Direct mapping] Doublecortin domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] Show all	890 aa 100.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.