Expression of C11orf24 in cancer - Summary - The Human Protein Atlas

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C11orf24

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C11orf24
Gene description	Chromosome 11 open reading frame 24
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues, including immune cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA012748
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), lung cancer (unfavourable) and glioma (unfavourable).
Renal cancer p<0.001 Lung cancer p<0.001 Glioma p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA012748

GENE INFORMATION
Gene name	C11orf24 (HGNC Symbol)
Synonyms	DM4E3
Description	Chromosome 11 open reading frame 24 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	68261335 - 68272001
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171067 (version 83.38)
Entrez gene	53838
UniProt	Q96F05 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96F05
Antibodypedia	C11orf24 antibodies

PROTEIN BROWSER

C11orf24-001	C11orf24-002	C11orf24-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C11orf24-001 ENSP00000307264 ENST00000304271	Q96F05 [Direct mapping] Uncharacterized protein C11orf24 A0A024R5K9 [Target identity:100%; Query identity:100%] Chromosome 11 open reading frame 24, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	449 aa 46.1 kDa	Yes	1
C11orf24-002 ENSP00000434144 ENST00000533310	E9PRU5 [Direct mapping] Uncharacterized protein C11orf24 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		114 aa 12.7 kDa	Yes	0
C11orf24-006 ENSP00000436765 ENST00000527280	E9PI63 [Direct mapping] Uncharacterized protein C11orf24 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		25 aa 2.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.