Expression of GIMAP8 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GIMAP8

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GIMAP8
Gene description	GTPase, IMAP family member 8
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enriched (HUVEC TERT2)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues. Additional positivity in endothelial cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA014474 , HPA017765
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in testis cancer (unfavourable).
Testis cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA014474	HPA017765

GENE INFORMATION
Gene name	GIMAP8 (HGNC Symbol)
Synonyms	DKFZp667I133, hIAN6, IAN9
Description	GTPase, IMAP family member 8 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q36.1
Chromosome location (bp)	150450630 - 150479392
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171115 (version 83.38)
Entrez gene	155038
UniProt	Q8ND71 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8ND71
Antibodypedia	GIMAP8 antibodies

PROTEIN BROWSER

GIMAP8-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GIMAP8-001 ENSP00000305107 ENST00000307271	Q8ND71 [Direct mapping] GTPase IMAP family member 8 A0A090N8H2 [Target identity:100%; Query identity:100%] Immune associated nucleotide 6 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] Show all	665 aa 74.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.