We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cancer tissues generally displayed moderate cytoplasmic staining. Several cases of colorectal cancers and a few cases of for example prostate and endometrial cancers showed strong cytoplasmic staining. Skin cancers were weakly stained.
GENE INFORMATION
Gene name
NETO2 (HGNC Symbol)
Synonyms
FLJ10430, NEOT2
Description
Neuropilin (NRP) and tolloid (TLL)-like 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]