Expression of ZDHHC16 in cancer - Summary - The Human Protein Atlas

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ZDHHC16

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZDHHC16
Gene description	Zinc finger, DHHC-type containing 16
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several different tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Antibody staining in cells/structures not annotated, view images.
Reliability score	Uncertain based on 1 antibody. HPA039893
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039893

GENE INFORMATION
Gene name	ZDHHC16 (HGNC Symbol)
Synonyms	APH2
Description	Zinc finger, DHHC-type containing 16 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q24.1
Chromosome location (bp)	97446131 - 97457370
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171307 (version 83.38)
Entrez gene	84287
UniProt	Q969W1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q969W1
Antibodypedia	ZDHHC16 antibodies

PROTEIN BROWSER

ZDHHC16-003	ZDHHC16-004	ZDHHC16-005	ZDHHC16-006	ZDHHC16-007	ZDHHC16-009	ZDHHC16-010	ZDHHC16-013	ZDHHC16-016	ZDHHC16-017	ZDHHC16-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZDHHC16-003 ENSP00000359891 ENST00000370854	Q969W1 [Direct mapping] Probable palmitoyltransferase ZDHHC16 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	377 aa 43.6 kDa	Yes	4
ZDHHC16-004 ENSP00000345383 ENST00000352634	Q969W1 [Direct mapping] Probable palmitoyltransferase ZDHHC16 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	361 aa 41.8 kDa	Yes	4
ZDHHC16-005 ENSP00000323360 ENST00000353979	Q969W1 [Direct mapping] Probable palmitoyltransferase ZDHHC16 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	338 aa 38.9 kDa	Yes	4
ZDHHC16-006 ENSP00000304487 ENST00000345745	Q969W1 [Direct mapping] Probable palmitoyltransferase ZDHHC16 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	296 aa 34.3 kDa	No	2
ZDHHC16-007 ENSP00000359879 ENST00000370842	Q969W1 [Direct mapping] Probable palmitoyltransferase ZDHHC16 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	361 aa 41.8 kDa	Yes	4
ZDHHC16-009 ENSP00000400719 ENST00000414567	B1AMU5 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	213 aa 24.8 kDa	Yes	3
ZDHHC16-010 ENSP00000398532 ENST00000433086	B1AMT9 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	242 aa 28.1 kDa	No	2
ZDHHC16-013 ENSP00000359883 ENST00000370846	B1AMU0 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	307 aa 35 kDa	Yes	3
ZDHHC16-016 ENSP00000405240 ENST00000420089	H0Y6E9 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	319 aa 37.1 kDa	No	3
ZDHHC16-017 ENSP00000396286 ENST00000417044	H0Y536 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	301 aa 35 kDa	No	4
ZDHHC16-201 ENSP00000377357 ENST00000393760	Q969W1 [Direct mapping] Probable palmitoyltransferase ZDHHC16 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	377 aa 43.6 kDa	Yes	4

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The Human Protein Atlas

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