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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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RSL1D1
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    TISSUE

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    CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

RSL1D1

Gene description

Ribosomal L1 domain containing 1

Protein class

Predicted intracellular proteins
Ribosomal proteins

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nucleolar expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 1 antibody.
HPA043483
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PROGNOSTIC SUMMARY

Prognostic marker in liver cancer (unfavourable), head and neck cancer (unfavourable) and renal cancer (unfavourable).
Liver cancer p<0.001
Head and neck cancer p<0.001
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA043483

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissues showed moderate to strong nucleolar immunoreactivity.

GENE INFORMATION

Gene name

RSL1D1 (HGNC Symbol)

Synonyms

CSIG, DKFZP564M182, L12, PBK1, UTP30

Description

Ribosomal L1 domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

16

Cytoband

p13.13

Chromosome location (bp)

11833850 - 11851585

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171490 (version 83.38)

Entrez gene

26156

UniProt

O76021 (UniProt - Evidence at protein level)

neXtProt

NX_O76021

Antibodypedia

RSL1D1 antibodies

PROTEIN BROWSER

RSL1D1-001
RSL1D1-002
RSL1D1-008
RSL1D1-009
RSL1D1-011

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RSL1D1-001
ENSP00000460871
ENST00000571133
O76021 [Direct mapping]
Ribosomal L1 domain-containing protein 1
Show all
Ribosomal proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001649 [osteoblast differentiation]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0016020 [membrane]
GO:0032880 [regulation of protein localization]
GO:0042981 [regulation of apoptotic process]
GO:0044822 [poly(A) RNA binding]
GO:2000772 [regulation of cellular senescence]
Show all
490 aa
55 kDa
No 0
RSL1D1-002
ENSP00000347897
ENST00000355674
J3QSV6 [Direct mapping]
Ribosomal L1 domain-containing protein 1
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005730 [nucleolus]
Show all
430 aa
48.2 kDa
No 0
RSL1D1-008
ENSP00000459331
ENST00000573791
I3L234 [Direct mapping]
Ribosomal L1 domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
98 aa
11.6 kDa
No 0
RSL1D1-009
ENSP00000460343
ENST00000571988
I3L3C4 [Direct mapping]
Ribosomal L1 domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
158 aa
18.5 kDa
No 0
RSL1D1-011
ENSP00000460748
ENST00000573251
I3L3U9 [Direct mapping]
Ribosomal L1 domain-containing protein 1
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
Show all
296 aa
33.9 kDa
No 0

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