Expression of MROH2B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MROH2B

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MROH2B
Gene description	Maestro heat-like repeat family member 2B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (liver cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 1 antibody. HPA059457
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (liver cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA059457

GENE INFORMATION
Gene name	MROH2B (HGNC Symbol)
Synonyms	DKFZp781F0822, FLJ40243, HEATR7B2
Description	Maestro heat-like repeat family member 2B (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p13.1
Chromosome location (bp)	40998017 - 41071342
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171495 (version 83.38)
Entrez gene	133558
UniProt	Q7Z745 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z745
Antibodypedia	MROH2B antibodies

PROTEIN BROWSER

MROH2B-001	MROH2B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MROH2B-001 ENSP00000382476 ENST00000399564	Q7Z745 [Direct mapping] Maestro heat-like repeat-containing protein family member 2B Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005488 [binding] Show all	1585 aa 180.8 kDa	No	0
MROH2B-006 ENSP00000441504 ENST00000506092	F5GZ06 [Direct mapping] Maestro heat-like repeat-containing protein family member 2B Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005488 [binding] Show all	1140 aa 129.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.