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KLF17

GENERAL INFORMATION

Gene name

 KLF17

Gene description

 Kruppel-like factor 17

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (testis cancer)
HPA (cell line):Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, U-138 MG)
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Expression in testis.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Presumed off target binding observed and disregarded. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA024629
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (testis cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Testis cancer

STAINING SUMMARY
HPA024629

GENE INFORMATION

Gene name

 KLF17 (HGNC Symbol)

Synonyms

 FLJ40160, Zfp393, ZNF393

Description

 Kruppel-like factor 17 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p34.1

Chromosome location (bp)

 44118850 - 44135140

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000171872 (version 83.38)

Entrez gene

 128209

UniProt

 Q5JT82 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5JT82

Antibodypedia

 KLF17 antibodies

PROTEIN BROWSER
KLF17-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KLF17-001
ENSP00000361373
ENST00000372299
Q5JT82 [Direct mapping]
Krueppel-like factor 17
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0007276 [gamete generation]
GO:0044212 [transcription regulatory region DNA binding]
GO:0046872 [metal ion binding]
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 389 aa
42.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.