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FBXW10

GENERAL INFORMATION

Gene name

 FBXW10

Gene description

 F-box and WD repeat domain containing 10

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

 Evidence at transcript level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 FBXW10 (HGNC Symbol)

Synonyms

 C17orf1, C17orf1A, Fbw10, HREP, SM2SH2

Description

 F-box and WD repeat domain containing 10 (HGNC Symbol)

Entrez gene summary

 Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Chromosome

 17

Cytoband

 p11.2

Chromosome location (bp)

 18744024 - 18779349

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000171931 (version 83.38)

Entrez gene

 10517

UniProt

 Q5XX13 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q5XX13

Antibodypedia

 FBXW10 antibodies

PROTEIN BROWSER
FBXW10-001
FBXW10-002
FBXW10-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FBXW10-001
ENSP00000306937
ENST00000301938
Q5XX13 [Direct mapping]
F-box/WD repeat-containing protein 10
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 999 aa
114 kDa 		No 0
FBXW10-002
ENSP00000310382
ENST00000308799
Q5XX13 [Direct mapping]
F-box/WD repeat-containing protein 10
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 1061 aa
120.7 kDa 		No 0
FBXW10-003
ENSP00000379025
ENST00000395665
Q5XX13 [Direct mapping]
F-box/WD repeat-containing protein 10
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 1052 aa
119.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.