Expression of ZNF131 in cancer - Summary - The Human Protein Atlas

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ZNF131

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF131
Gene description	Zinc finger protein 131
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	9
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA007023
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA007023

GENE INFORMATION
Gene name	ZNF131 (HGNC Symbol)
Synonyms	pHZ-10, ZBTB35
Description	Zinc finger protein 131 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p12
Chromosome location (bp)	43065176 - 43192021
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172262 (version 83.38)
Entrez gene	7690
UniProt	P52739 (UniProt - Evidence at protein level)
neXtProt	NX_P52739
Antibodypedia	ZNF131 antibodies

PROTEIN BROWSER

ZNF131-004	ZNF131-007	ZNF131-008	ZNF131-009	ZNF131-011	ZNF131-012	ZNF131-013	ZNF131-014	ZNF131-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF131-004 ENSP00000427003 ENST00000507393	D6RD61 [Direct mapping] Zinc finger protein 131 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	79 aa 9 kDa	No	0
ZNF131-007 ENSP00000305804 ENST00000306938	P52739 [Direct mapping] Zinc finger protein 131 A0A024R087 [Target identity:100%; Query identity:100%] HCG36935, isoform CRA_b Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	589 aa 67.3 kDa	No	0
ZNF131-008 ENSP00000422079 ENST00000515326	D6R9I2 [Direct mapping] Zinc finger protein 131 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	265 aa 30.2 kDa	No	0
ZNF131-009 ENSP00000426504 ENST00000509156	P52739 [Direct mapping] Zinc finger protein 131 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	623 aa 71.4 kDa	No	0
ZNF131-011 ENSP00000421246 ENST00000509634	P52739 [Direct mapping] Zinc finger protein 131 A0A024R087 [Target identity:100%; Query identity:100%] HCG36935, isoform CRA_b Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	589 aa 67.3 kDa	No	0
ZNF131-012 ENSP00000423945 ENST00000505606	P52739 [Direct mapping] Zinc finger protein 131 A0A024R087 [Target identity:100%; Query identity:100%] HCG36935, isoform CRA_b Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	589 aa 67.3 kDa	No	0
ZNF131-013 ENSP00000422659 ENST00000508259	D6RBK1 [Direct mapping] Zinc finger protein 131 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	151 aa 17.7 kDa	No	0
ZNF131-014 ENSP00000424771 ENST00000509341	D6RAT8 [Direct mapping] Zinc finger protein 131 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	139 aa 16.3 kDa	No	0
ZNF131-015 ENSP00000425722 ENST00000509931	D6RJ09 [Direct mapping] Zinc finger protein 131 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	66 aa 7.7 kDa	No	0

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