Expression of DNAJB7 in cancer - Summary - The Human Protein Atlas

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DNAJB7

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DNAJB7
Gene description	DnaJ (Hsp40) homolog, subfamily B, member 7
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA000534
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA000534

GENE INFORMATION
Gene name	DNAJB7 (HGNC Symbol)
Synonyms	HSC3
Description	DnaJ (Hsp40) homolog, subfamily B, member 7 (HGNC Symbol)
Entrez gene summary	The protein encoded by this intronless gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain.[provided by RefSeq, Mar 2011]
Chromosome	22
Cytoband	q13.2
Chromosome location (bp)	40859549 - 40862126
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000172404 (version 83.38)
Entrez gene	150353
UniProt	Q7Z6W7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z6W7
Antibodypedia	DNAJB7 antibodies

PROTEIN BROWSER

DNAJB7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DNAJB7-001 ENSP00000307197 ENST00000307221	Q7Z6W7 [Direct mapping] DnaJ homolog subfamily B member 7 Show all	Predicted intracellular proteins Show all	GO:0051087 [chaperone binding] Show all	309 aa 35.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.