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ZNF24

GENERAL INFORMATION

Gene name

 ZNF24

Gene description

 Zinc finger protein 24

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA024062 , CAB025642
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA024062
CAB025642

GENE INFORMATION

Gene name

 ZNF24 (HGNC Symbol)

Synonyms

 KOX17, Zfp191, ZNF191, ZSCAN3

Description

 Zinc finger protein 24 (HGNC Symbol)

Entrez gene summary

Chromosome

 18

Cytoband

 q12.2

Chromosome location (bp)

 35332212 - 35345482

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172466 (version 83.38)

Entrez gene

 7572

UniProt

 P17028 (UniProt - Evidence at protein level)

neXtProt

 NX_P17028

Antibodypedia

 ZNF24 antibodies

PROTEIN BROWSER
ZNF24-001
ZNF24-002
ZNF24-003
ZNF24-004
ZNF24-005
ZNF24-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF24-001
ENSP00000261332
ENST00000261332
P17028 [Direct mapping]
Zinc finger protein 24
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0042552 [myelination]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 368 aa
42.2 kDa 		No 0
ZNF24-002
ENSP00000382015
ENST00000399061
P17028 [Direct mapping]
Zinc finger protein 24
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0042552 [myelination]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 368 aa
42.2 kDa 		No 0
ZNF24-003
ENSP00000467655
ENST00000589881
P17028 [Direct mapping]
Zinc finger protein 24
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0042552 [myelination]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
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 193 aa
22.4 kDa 		No 0
ZNF24-004
ENSP00000467432
ENST00000590140
K7EPL1 [Direct mapping]
Zinc finger protein 24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
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 138 aa
16 kDa 		No 0
ZNF24-005
ENSP00000467608
ENST00000589539
K7EPZ8 [Direct mapping]
Zinc finger protein 24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
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 102 aa
11.9 kDa 		No 0
ZNF24-006
ENSP00000467924
ENST00000593130
K7EQP8 [Direct mapping]
Zinc finger protein 24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
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 96 aa
11.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.