Expression of AGAP5 in cancer - Summary - The Human Protein Atlas

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AGAP5

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	AGAP5
Gene description	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA042490
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042490

GENE INFORMATION
Gene name	AGAP5 (HGNC Symbol)
Synonyms	CTGLF2, Em:AC073389.1
Description	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q22.2
Chromosome location (bp)	73674285 - 73698159
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000172650 (version 83.38)
Entrez gene	729092
UniProt	A6NIR3 (UniProt - Evidence at transcript level)
neXtProt	NX_A6NIR3
Antibodypedia	AGAP5 antibodies

PROTEIN BROWSER

AGAP5-001	AGAP5-003	AGAP5-201	AGAP5-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AGAP5-001 ENSP00000402792 ENST00000443782	J3KQL4 [Direct mapping] Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 Show all	Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0043547 [positive regulation of GTPase activity] GO:0046872 [metal ion binding] Show all	663 aa 73 kDa	No	0
AGAP5-003 ENSP00000363207 ENST00000374094	A6NIR3 [Direct mapping] Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0043547 [positive regulation of GTPase activity] GO:0046872 [metal ion binding] Show all	686 aa 75.5 kDa	No	0
AGAP5-201 ENSP00000486918 ENST00000581191	A0A0D9SFU9 [Direct mapping] Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 Show all	Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0043547 [positive regulation of GTPase activity] Show all	686 aa 75.5 kDa	No	0
AGAP5-202 ENSP00000483632 ENST00000621690	A0A087X0S6 [Direct mapping] Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 Show all	Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] Show all	658 aa 72.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.