Expression of MS4A10 in cancer - Summary - The Human Protein Atlas

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MS4A10

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MS4A10
Gene description	Membrane-spanning 4-domains, subfamily A, member 10
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (duodenum, small intestine)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA014778
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA014778

GENE INFORMATION
Gene name	MS4A10 (HGNC Symbol)
Synonyms	CD20L7, MS4A9
Description	Membrane-spanning 4-domains, subfamily A, member 10 (HGNC Symbol)
Entrez gene summary	Most MS4A genes, including MS4A10, encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons.[supplied by OMIM, Apr 2004]
Chromosome	11
Cytoband	q12.2
Chromosome location (bp)	60785348 - 60801305
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000172689 (version 83.38)
Entrez gene	341116
UniProt	Q96PG2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96PG2
Antibodypedia	MS4A10 antibodies

PROTEIN BROWSER

MS4A10-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MS4A10-001 ENSP00000311862 ENST00000308287	Q96PG2 [Direct mapping] Membrane-spanning 4-domains subfamily A member 10 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	267 aa 29.7 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.