Expression of FADS6 in cancer - Summary - The Human Protein Atlas

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FADS6

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FADS6
Gene description	Fatty acid desaturase 6
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (liver cancer)
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (epididymis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA016802
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (liver cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA016802

GENE INFORMATION
Gene name	FADS6
Synonyms
Description	Fatty acid desaturase 6 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	74877299 - 74893781
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000172782 (version 83.38)
Entrez gene	283985
UniProt
neXtProt
Antibodypedia	FADS6 antibodies

PROTEIN BROWSER

FADS6-001	FADS6-003	FADS6-004	FADS6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FADS6-001 ENSP00000481684 ENST00000612771	A0A087WYB9 [Direct mapping] Fatty acid desaturase 6 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0006629 [lipid metabolic process] Show all	368 aa 41.8 kDa	No	5
FADS6-003 ENSP00000464267 ENST00000579663	J3QRK6 [Direct mapping] Fatty acid desaturase 6 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0006629 [lipid metabolic process] GO:0016021 [integral component of membrane] Show all	219 aa 24.3 kDa	No	2
FADS6-004 ENSP00000480385 ENST00000621859	A0A087WWN9 [Direct mapping] Fatty acid desaturase 6 Show all	Predicted intracellular proteins Show all		123 aa 13.6 kDa	No	0
FADS6-201 ENSP00000478413 ENST00000614223	A0A087WU67 [Direct mapping] Fatty acid desaturase 6; Fatty acid desaturase domain family, member 6, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0006629 [lipid metabolic process] GO:0016021 [integral component of membrane] Show all	350 aa 39.8 kDa	No	5

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.