Expression of MYEOV in cancer - Summary - The Human Protein Atlas

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MYEOV

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MYEOV
Gene description	Myeloma overexpressed
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (A-431, A549, U-2 OS)
HPA (normal tissue):	Group enriched (adipose tissue, breast, esophagus, skin, stomach)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA012949
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (unfavourable), renal cancer (unfavourable) and lung cancer (unfavourable).
Pancreatic cancer p<0.001 Renal cancer p<0.001 Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA012949

GENE INFORMATION
Gene name	MYEOV (HGNC Symbol)
Synonyms	OCIM
Description	Myeloma overexpressed (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.3
Chromosome location (bp)	69294138 - 69367726
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000172927 (version 83.38)
Entrez gene	26579
UniProt	Q96EZ4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96EZ4
Antibodypedia	MYEOV antibodies

PROTEIN BROWSER

MYEOV-001	MYEOV-002	MYEOV-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYEOV-001 ENSP00000438100 ENST00000535407	F5H0B3 [Direct mapping] Myeloma-overexpressed gene protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		255 aa 27.1 kDa	No	1
MYEOV-002 ENSP00000412482 ENST00000441339	Q96EZ4 [Direct mapping] Myeloma-overexpressed gene protein A0A024R5F1 [Target identity:100%; Query identity:100%] Myeloma overexpressed gene (In a subset of t(1114) positive multiple myelomas), isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		313 aa 33.6 kDa	No	1
MYEOV-004 ENSP00000308330 ENST00000308946	Q96EZ4 [Direct mapping] Myeloma-overexpressed gene protein A0A024R5F1 [Target identity:100%; Query identity:100%] Myeloma overexpressed gene (In a subset of t(1114) positive multiple myelomas), isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		313 aa 33.6 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.