Expression of CCDC96 in cancer - Summary - The Human Protein Atlas

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CCDC96

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC96
Gene description	Coiled-coil domain containing 96
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in ciliated cells and cells of seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA047546
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), endometrial cancer (favourable) and pancreatic cancer (favourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047546

GENE INFORMATION
Gene name	CCDC96 (HGNC Symbol)
Synonyms	FLJ90575
Description	Coiled-coil domain containing 96 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p16.1
Chromosome location (bp)	7040849 - 7042939
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173013 (version 83.38)
Entrez gene	257236
UniProt	Q2M329 (UniProt - Evidence at transcript level)
neXtProt	NX_Q2M329
Antibodypedia	CCDC96 antibodies

PROTEIN BROWSER

CCDC96-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC96-001 ENSP00000309285 ENST00000310085	Q2M329 [Direct mapping] Coiled-coil domain-containing protein 96 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] Show all	555 aa 62.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.