We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Most of the malignant tissues exhibited weak to moderate cytoplasmic staining often combined with membranous positivity. Malignant carcinoid, glioma and lymphoma as well as urothelial cancers were negative.
GENE INFORMATION
Gene name
MMRN2 (HGNC Symbol)
Synonyms
EMILIN3, EndoGlyx-1, FLJ13465
Description
Multimerin 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]