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ZNF622

GENERAL INFORMATION

Gene name

 ZNF622

Gene description

 Zinc finger protein 622

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA036514 , HPA036515
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036514
HPA036515

GENE INFORMATION

Gene name

 ZNF622 (HGNC Symbol)

Synonyms

 MGC17552, MGC2485, ZPR9

Description

 Zinc finger protein 622 (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 p15.1

Chromosome location (bp)

 16451519 - 16465792

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173545 (version 83.38)

Entrez gene

 90441

UniProt

 Q969S3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q969S3

Antibodypedia

 ZNF622 antibodies

PROTEIN BROWSER
ZNF622-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF622-001
ENSP00000310042
ENST00000308683
Q969S3 [Direct mapping]
Zinc finger protein 622
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0008270 [zinc ion binding]
GO:0008631 [intrinsic apoptotic signaling pathway in response to oxidative stress]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0030687 [preribosome, large subunit precursor]
GO:0033674 [positive regulation of kinase activity]
GO:0042273 [ribosomal large subunit biogenesis]
GO:0043065 [positive regulation of apoptotic process]
GO:0043410 [positive regulation of MAPK cascade]
GO:0044822 [poly(A) RNA binding]
GO:0046330 [positive regulation of JNK cascade]
GO:0046872 [metal ion binding]
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 477 aa
54.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.