Expression of CCDC106 in cancer - Summary - The Human Protein Atlas

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CCDC106

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC106
Gene description	Coiled-coil domain containing 106
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (HEK93)
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA041925 , HPA043219
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and pancreatic cancer (favourable).
Renal cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041925	HPA043219

GENE INFORMATION
Gene name	CCDC106 (HGNC Symbol)
Synonyms	HSU79303
Description	Coiled-coil domain containing 106 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.42
Chromosome location (bp)	55641062 - 55653161
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173581 (version 83.38)
Entrez gene	29903
UniProt	Q9BWC9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BWC9
Antibodypedia	CCDC106 antibodies

PROTEIN BROWSER

CCDC106-001	CCDC106-002	CCDC106-003	CCDC106-004	CCDC106-006	CCDC106-007	CCDC106-008	CCDC106-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC106-001 ENSP00000309681 ENST00000308964	Q9BWC9 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	280 aa 32 kDa	No	0
CCDC106-002 ENSP00000465757 ENST00000586790	Q9BWC9 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	280 aa 32 kDa	No	0
CCDC106-003 ENSP00000466870 ENST00000591578	Q9BWC9 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	280 aa 32 kDa	No	0
CCDC106-004 ENSP00000468539 ENST00000588740	Q9BWC9 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	280 aa 32 kDa	No	0
CCDC106-006 ENSP00000468521 ENST00000593069	K7ES29 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all		45 aa 5.4 kDa	No	0
CCDC106-007 ENSP00000468077 ENST00000587213	K7ER22 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all		39 aa 4.6 kDa	No	0
CCDC106-008 ENSP00000466521 ENST00000591241	K7EMI9 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] Show all	245 aa 27.9 kDa	No	0
CCDC106-009 ENSP00000466597 ENST00000592996	K7EMP7 [Direct mapping] Coiled-coil domain-containing protein 106 Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	172 aa 19.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.