Fields »
ABOUT
HELP
BLOG
SULT1B1

GENERAL INFORMATION

Gene name

 SULT1B1

Gene description

 Sulfotransferase family, cytosolic, 1B, member 1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (colorectal cancer, liver cancer, pancreatic cancer, stomach cancer)
HPA (cell line):Group enriched (HUVEC TERT2, TIME, U-2197)
HPA (normal tissue):Group enriched (colon, duodenum, rectum, small intestine, stomach)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression with a granular pattern in intestinal tract.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA002107
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (colorectal cancer, liver cancer, pancreatic cancer, stomach cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Endometrial cancer

STAINING SUMMARY
HPA002107

GENE INFORMATION

Gene name

 SULT1B1 (HGNC Symbol)

Synonyms

 ST1B2

Description

 Sulfotransferase family, cytosolic, 1B, member 1 (HGNC Symbol)

Entrez gene summary

 Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 q13.3

Chromosome location (bp)

 69721162 - 69787961

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173597 (version 83.38)

Entrez gene

 27284

UniProt

 O43704 (UniProt - Evidence at protein level)

neXtProt

 NX_O43704

Antibodypedia

 SULT1B1 antibodies

PROTEIN BROWSER
SULT1B1-001
SULT1B1-002
SULT1B1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SULT1B1-001
ENSP00000308770
ENST00000310613
O43704 [Direct mapping]
Sulfotransferase family cytosolic 1B member 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004062 [aryl sulfotransferase activity]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0006576 [cellular biogenic amine metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0008146 [sulfotransferase activity]
GO:0008202 [steroid metabolic process]
GO:0009812 [flavonoid metabolic process]
GO:0018958 [phenol-containing compound metabolic process]
GO:0030855 [epithelial cell differentiation]
GO:0042403 [thyroid hormone metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process]
GO:0051923 [sulfation]
Show all
 296 aa
34.9 kDa 		No 0
SULT1B1-002
ENSP00000425464
ENST00000510821
D6RD70 [Direct mapping]
Sulfotransferase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008146 [sulfotransferase activity]
GO:0008152 [metabolic process]
Show all
 155 aa
17.8 kDa 		No 0
SULT1B1-003
ENSP00000427536
ENST00000512870
D6RIA8 [Direct mapping]
Sulfotransferase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008146 [sulfotransferase activity]
GO:0008152 [metabolic process]
Show all
 73 aa
8.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.