Expression of CXorf23 in cancer - Summary - The Human Protein Atlas

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CXorf23

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CXorf23
Gene description	Chromosome X open reading frame 23
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA027215
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PROGNOSTIC SUMMARY
Prognostic marker in lung cancer (favourable) and urothelial cancer (favourable).
Lung cancer p<0.001 Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027215

GENE INFORMATION
Gene name	CXorf23
Synonyms
Description	Chromosome X open reading frame 23 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	p22.12
Chromosome location (bp)	19912860 - 19970298
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173681 (version 83.38)
Entrez gene	256643
UniProt	A2AJT9 (UniProt - Evidence at protein level)
neXtProt	NX_A2AJT9
Antibodypedia	CXorf23 antibodies

PROTEIN BROWSER

CXorf23-001	CXorf23-002	CXorf23-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CXorf23-001 ENSP00000369009 ENST00000379687	A2AJT9 [Direct mapping] Uncharacterized protein CXorf23 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] Show all	682 aa 80.4 kDa	No	0
CXorf23-002 ENSP00000342104 ENST00000340625	H7BXX2 [Direct mapping] Uncharacterized protein CXorf23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		234 aa 26.6 kDa	No	0
CXorf23-006 ENSP00000369004 ENST00000379682	A2AJT9 [Direct mapping] Uncharacterized protein CXorf23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] Show all	711 aa 83.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.