Expression of C11orf80 in cancer - Summary - The Human Protein Atlas

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C11orf80

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C11orf80
Gene description	Chromosome 11 open reading frame 80
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA038932 , HPA038933
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038932	HPA038933

GENE INFORMATION
Gene name	C11orf80 (HGNC Symbol)
Synonyms	FLJ22531
Description	Chromosome 11 open reading frame 80 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	66744451 - 66843328
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173715 (version 83.38)
Entrez gene	79703
UniProt	Q8N6T0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N6T0
Antibodypedia	C11orf80 antibodies

PROTEIN BROWSER

C11orf80-001	C11orf80-002	C11orf80-004	C11orf80-007	C11orf80-008	C11orf80-009	C11orf80-012	C11orf80-016	C11orf80-019	C11orf80-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C11orf80-001 ENSP00000434804 ENST00000532565	H0YE21 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted intracellular proteins Show all		459 aa 51.2 kDa	No	0
C11orf80-002 ENSP00000444319 ENST00000540737	B4DXL1 [Direct mapping] Uncharacterized protein C11orf80; cDNA FLJ55941 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all		511 aa 57 kDa	No	0
C11orf80-004 ENSP00000434648 ENST00000525449		MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all		485 aa 54.1 kDa	No	0
C11orf80-007 ENSP00000431578 ENST00000527634	E9PKM2 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted intracellular proteins Show all		460 aa 51.3 kDa	No	0
C11orf80-008 ENSP00000437319 ENST00000534325	E9PMU2 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted intracellular proteins Show all		15 aa 1.5 kDa	No	0
C11orf80-009 ENSP00000434960 ENST00000524551	E9PMI8 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted intracellular proteins Show all		129 aa 14.2 kDa	No	0
C11orf80-012 ENSP00000433032 ENST00000531415	H0YD55 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted intracellular proteins Show all		210 aa 22.9 kDa	No	0
C11orf80-016 ENSP00000433869 ENST00000532089	H0YDL3 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted intracellular proteins Show all		150 aa 16.5 kDa	No	0
C11orf80-019 ENSP00000432039 ENST00000525908	Q8N6T0 [Direct mapping] Uncharacterized protein C11orf80 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		677 aa 74.6 kDa	No	0
C11orf80-201 ENSP00000354227 ENST00000360962	A0A0A0MRH1 [Direct mapping] Uncharacterized protein C11orf80 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		572 aa 63.3 kDa	No	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.