Fields »
ABOUT
HELP
BLOG
TOMM20

GENERAL INFORMATION

Gene name

 TOMM20

Gene description

 Translocase of outer mitochondrial membrane 20 homolog (yeast)

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression with a granular pattern in all tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA011562 , CAB005585
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA011562
CAB005585

GENE INFORMATION

Gene name

 TOMM20 (HGNC Symbol)

Synonyms

 KIAA0016, MAS20, MOM19, TOM20

Description

 Translocase of outer mitochondrial membrane 20 homolog (yeast) (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q42.3

Chromosome location (bp)

 235109336 - 235128936

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173726 (version 83.38)

Entrez gene

 9804

UniProt

 Q15388 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15388

Antibodypedia

 TOMM20 antibodies

PROTEIN BROWSER
TOMM20-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TOMM20-001
ENSP00000355566
ENST00000366607
Q15388 [Direct mapping]
Mitochondrial import receptor subunit TOM20 homolog
A0A024R3W2 [Target identity:100%; Query identity:100%]
Translocase of outer mitochondrial membrane 20 homolog (Yeast), isoform CRA_a
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000423 [macromitophagy]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005740 [mitochondrial envelope]
GO:0005741 [mitochondrial outer membrane]
GO:0005742 [mitochondrial outer membrane translocase complex]
GO:0006605 [protein targeting]
GO:0006626 [protein targeting to mitochondrion]
GO:0006886 [intracellular protein transport]
GO:0015266 [protein channel activity]
GO:0015450 [P-P-bond-hydrolysis-driven protein transmembrane transporter activity]
GO:0016031 [tRNA import into mitochondrion]
GO:0016236 [macroautophagy]
GO:0030150 [protein import into mitochondrial matrix]
GO:0030943 [mitochondrion targeting sequence binding]
GO:0031307 [integral component of mitochondrial outer membrane]
GO:0044233 [ER-mitochondrion membrane contact site]
GO:0044267 [cellular protein metabolic process]
GO:0051082 [unfolded protein binding]
GO:0070096 [mitochondrial outer membrane translocase complex assembly]
Show all
 145 aa
16.3 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.