Expression of CYB561D1 in cancer - Summary - The Human Protein Atlas

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CYB561D1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CYB561D1
Gene description	Cytochrome b561 family, member D1
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and/or nuclear expression in selected tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA027028
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable), renal cancer (favourable) and head and neck cancer (favourable).
Pancreatic cancer p<0.001 Renal cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027028

GENE INFORMATION
Gene name	CYB561D1 (HGNC Symbol)
Synonyms	FLJ39035, FLJ44753
Description	Cytochrome b561 family, member D1 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	109494052 - 109502932
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174151 (version 83.38)
Entrez gene	284613
UniProt	Q8N8Q1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N8Q1
Antibodypedia	CYB561D1 antibodies

PROTEIN BROWSER

CYB561D1-001	CYB561D1-002	CYB561D1-003	CYB561D1-004	CYB561D1-006	CYB561D1-007	CYB561D1-008	CYB561D1-009	CYB561D1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYB561D1-001 ENSP00000413530 ENST00000420578	Q8N8Q1 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	229 aa 25.4 kDa	No	6
CYB561D1-002 ENSP00000416898 ENST00000430195	Q8N8Q1 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	128 aa 14.2 kDa	No	1
CYB561D1-003 ENSP00000309324 ENST00000310611	Q8N8Q1 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	133 aa 14.3 kDa	No	1
CYB561D1-004 ENSP00000435819 ENST00000496961	E9PIJ2 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	64 aa 6.9 kDa	No	1
CYB561D1-006 ENSP00000435802 ENST00000533024	E9PIK3 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted intracellular proteins Show all		54 aa 5.8 kDa	No	0
CYB561D1-007 ENSP00000433095 ENST00000527072	E9PM70 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	55 aa 5.9 kDa	No	1
CYB561D1-008 ENSP00000434344 ENST00000528785	E9PQU0 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0055114 [oxidation-reduction process] Show all	231 aa 25.6 kDa	No	6
CYB561D1-009 ENSP00000358884 ENST00000369868	Q8N8Q1 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	251 aa 27.7 kDa	No	6
CYB561D1-010 ENSP00000377312 ENST00000393709	Q8N8Q1 [Direct mapping] Cytochrome b561 domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	172 aa 19.3 kDa	No	4

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The Human Protein Atlas

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