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CHRNA9

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GENERAL INFORMATION

Gene name

 CHRNA9

Gene description

 Cholinergic receptor, nicotinic, alpha 9 (neuronal)

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enriched (U-87 MG)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (U-87 MG)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 CHRNA9 (HGNC Symbol)

Synonyms

 NACHRA9

Description

 Cholinergic receptor, nicotinic, alpha 9 (neuronal) (HGNC Symbol)

Entrez gene summary

 This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. [provided by RefSeq, Feb 2012]

Chromosome

 4

Cytoband

 p14

Chromosome location (bp)

 40335329 - 40355217

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000174343 (version 83.38)

Entrez gene

 55584

UniProt

 Q9UGM1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UGM1

Antibodypedia

 CHRNA9 antibodies

PROTEIN BROWSER
CHRNA9-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CHRNA9-001
ENSP00000312663
ENST00000310169
Q9UGM1 [Direct mapping]
Neuronal acetylcholine receptor subunit alpha-9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Show all
GO:0004889 [acetylcholine-activated cation-selective channel activity]
GO:0005230 [extracellular ligand-gated ion channel activity]
GO:0005262 [calcium channel activity]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0005892 [acetylcholine-gated channel complex]
GO:0006810 [transport]
GO:0006811 [ion transport]
GO:0006812 [cation transport]
GO:0007165 [signal transduction]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007268 [synaptic transmission]
GO:0007271 [synaptic transmission, cholinergic]
GO:0007274 [neuromuscular synaptic transmission]
GO:0007605 [sensory perception of sound]
GO:0015464 [acetylcholine receptor activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0022848 [acetylcholine-gated cation channel activity]
GO:0030054 [cell junction]
GO:0035094 [response to nicotine]
GO:0042166 [acetylcholine binding]
GO:0042391 [regulation of membrane potential]
GO:0042472 [inner ear morphogenesis]
GO:0043005 [neuron projection]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0050877 [neurological system process]
GO:0050910 [detection of mechanical stimulus involved in sensory perception of sound]
GO:0070588 [calcium ion transmembrane transport]
GO:0098655 [cation transmembrane transport]
Show all
 479 aa
54.8 kDa 		Yes 4

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.