Fields »
ABOUT
HELP
BLOG
ABRA

GENERAL INFORMATION

Gene name

 ABRA

Gene description

 Actin binding Rho activating protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Group enriched (heart muscle, skeletal muscle)

Protein evidence

 Evidence at transcript level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA017724
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA017724

GENE INFORMATION

Gene name

 ABRA (HGNC Symbol)

Synonyms

 STARS

Description

 Actin binding Rho activating protein (HGNC Symbol)

Entrez gene summary

Chromosome

 8

Cytoband

 q23.1

Chromosome location (bp)

 106759483 - 106770245

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000174429 (version 83.38)

Entrez gene

 137735

UniProt

 Q8N0Z2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8N0Z2

Antibodypedia

 ABRA antibodies

PROTEIN BROWSER
ABRA-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ABRA-001
ENSP00000311436
ENST00000311955
Q8N0Z2 [Direct mapping]
Actin-binding Rho-activating protein
Show all
Predicted intracellular proteins
Show all
GO:0000060 [protein import into nucleus, translocation]
GO:0003779 [actin binding]
GO:0005886 [plasma membrane]
GO:0006351 [transcription, DNA-templated]
GO:0015629 [actin cytoskeleton]
GO:0030016 [myofibril]
GO:0030017 [sarcomere]
GO:0035025 [positive regulation of Rho protein signal transduction]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
Show all
 381 aa
43.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.