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TTC9B

GENERAL INFORMATION

Gene name

 TTC9B

Gene description

 Tetratricopeptide repeat domain 9B

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (glioma)
HPA (cell line):Cell line enriched (SCLC-21H)
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in CNS, renal tubules and adrenal gland.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

 Uncertain based on 1 antibody.
HPA042496
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042496

GENE INFORMATION

Gene name

 TTC9B (HGNC Symbol)

Synonyms

 FLJ30373

Description

 Tetratricopeptide repeat domain 9B (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 q13.2

Chromosome location (bp)

 40216058 - 40218399

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000174521 (version 83.38)

Entrez gene

 148014

UniProt

 Q8N6N2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8N6N2

Antibodypedia

 TTC9B antibodies

PROTEIN BROWSER
TTC9B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TTC9B-001
ENSP00000311760
ENST00000311308
Q8N6N2 [Direct mapping]
Tetratricopeptide repeat protein 9B
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
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GO:0000413 [protein peptidyl-prolyl isomerization]
GO:0003674 [molecular_function]
GO:0003755 [peptidyl-prolyl cis-trans isomerase activity]
GO:0005515 [protein binding]
GO:0005528 [FK506 binding]
GO:0005575 [cellular_component]
GO:0005737 [cytoplasm]
GO:0005789 [endoplasmic reticulum membrane]
GO:0008150 [biological_process]
GO:0061077 [chaperone-mediated protein folding]
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 239 aa
25.9 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.